1,2-propanediol


1,2-dihydroxypropane; methylethylene glycol; methyl glycol; (±)-1,2-propanediol; 1,2-propanediol; propane-1,2-diol; propylene glycol; α-propylene glycol; 1,2-propylene glycol
Links:🌍 Wikipedia, 📖 PubMed
MeSH:Solvents
CAS RN:[57-55-6]
Formula:C3H8O2; 76.10 g/mol
InChiKey:DNIAPMSPPWPWGF-UHFFFAOYSA-N
SMILES:OCC(O)C
Molecular structure of 1,2-propanediol
Use:antifreeze agent; chemical intermediate in manufacture of synthetic drying oil and treatment of vegetable oils; component of brake fluid compositions; humectant for magnesium foundry sands; inhibitor of mold growth and fermentation; lubricant in refrigerating machines; moistening agent for tobacco and lead pencils; plasticizer and hygroscopic agent for cellulose products; plasticizer in adhesives; processing of films, leather, paints, paper, and resins; solvent and spreading agent in dyes; thickener solvent, and spreading agent in inks
Toxicology (LD50):25 000 mg/Kg (dog, iv); 18 350 mg/Kg(guinea~pig, or); 18 900 mg/Kg(guinea~pig, or); 9 730 mg/Kg(mouse, ip); 5 000 mg/Kg(mouse, iv); 8 000 mg/Kg(mouse, iv); 2 200 mg/Kg(mouse, or); 23 900 mg/Kg(mouse, or); 10 500 mg/Kg(mouse, sc); 4 100 mg/Kg(rabbit, iv); 6 200 mg/Kg(rabbit, iv); 19 200 mg/Kg(rabbit, or); 13 400 mg/Kg(rat, im); 20 000 mg/Kg(rat, im); 13 000 mg/Kg(rat, ip); 21 000 mg/Kg(rat, or); 32 200 mg/Kg(rat, or); 24 900 mg/Kg(rat, sc); 28 000 mg/Kg(rat, sc)
Density:1.036 g/mL
Molar volume:73.4 mL/mol
Refractive index:1.431
Molecular refractive power:19.01 mL/mol
Dielectric constant:32.00
Dipole moment:2.27 D
Melting point:-60 °C
Boiling point:187 °C
Vapour pressure:0 Torr
Antoine equation
P(Torr) vs T(°C)
Vapour pressure vs temperature
Surface tension:72.00 dyn/cm
Viscosity:54.00 cP
Critical temperature:351 °C
Critical pressure:60.2 atm
Evaporation rate (butyl acetate):0.0
Solubility in water:100 % w/w
Solubility of water:100 % w/w
Log10 partition water / activated carbon:1.43
Log10 partition octanol / water:-1.35
Dimroth ET:54.1
Hansen solubility parameter:δd: 8.2 (cal/mL)^0.5   δp: 4.6 (cal/mL)^0.5   δh: 11.4 (cal/mL)^0.5
Immiscible with:
2,6,8-trimethyl-4-nonanone,    2,6-dimethyl-4-heptanone,    N,N-dipropylaniline,    dibenzyl ether,    dihexyl ether,    ethyl (E)-3-phenylprop-2-enoate,    ethyl phenylacetate,    heptyl acetate
Miscible with:
(E)-3-phenyl-2-propenal,    1-amino-2-propanol,    1-phenylethan-1-amine,    1-tetradecanol,    2-(1-phenylethylamino)ethanol,    2-(2-hydroxyethyl-(1-phenylethyl)amino)ethanol,    2-ethoxyaniline,    2-ethylbutanoic acid,    2-methylphenol,    2-phenylethylamine,    3-heptanol,    3-methyl-2-butanone,    3-methylbutyl acetate,    4-methoxybenzaldehyde,    4-methylpentanoic acid,    5-ethyl-2-methylpyridine,    N,N-diethylformamide,    N-(2-aminoethyl)ethane-1,2-diamine,    a-methylbenzyldimethylamine,    dibutylamine,    diisopropylamine,    dipentylamine,    ethanol,    ethyl chloroacetate,    hexanenitrile,    pyridine,    salicylaldehyde,    tributyl phosphate,    trichloromethane,    triethylenetetramine
Specific heat capacity:45.0 cal/molK

Isomers

dimethoxymethane
Molecular structure of dimethoxymethane
1-hydroperoxypropane
Molecular structure of 1-hydroperoxypropane
2-hydroperoxypropane
Molecular structure of 2-hydroperoxypropane
2-methoxyethanol
Molecular structure of 2-methoxyethanol
methylperoxyethane
Molecular structure of methylperoxyethane
(R)-(-)-1,2-propanediol
Molecular structure of (R)-(-)-1,2-propanediol
1,2-propanediol
Molecular structure of 1,2-propanediol
1,3-propanediol
Molecular structure of 1,3-propanediol
(~S)-(+)-1,2-propanediol
Molecular structure of (S)-(+)-1,2-propanediol